姓名：陳依華
職務(wù)、職稱：系主任、教授、博導(dǎo)
系別： 預(yù)防醫(yī)學(xué)系
聯(lián)系電話：027-68759956
郵箱：wchunhong027@whu.edu.cn
個(gè)人簡(jiǎn)介：
教育經(jīng)歷：1986.7獲華中科技大學(xué)同濟(jì)醫(yī)學(xué)院預(yù)防醫(yī)學(xué)專業(yè)學(xué)士學(xué)位；碩士研究生（1988.9-1991.7）就讀于復(fù)旦大學(xué)醫(yī)學(xué)院（原上海醫(yī)科大學(xué)）營(yíng)養(yǎng)與食品衛(wèi)生專業(yè)；2004年獲武漢大學(xué)醫(yī)學(xué)院博士學(xué)位。
社會(huì)兼職：湖北省營(yíng)養(yǎng)學(xué)會(huì)副理事長(zhǎng)、湖北省預(yù)防醫(yī)學(xué)會(huì)理事、湖北省毒理學(xué)會(huì)常務(wù)理事、武漢市營(yíng)養(yǎng)學(xué)會(huì)副理事長(zhǎng)；中國(guó)毒理學(xué)會(huì)免疫專業(yè)委員會(huì)理事；國(guó)家自然基金評(píng)審專家、湖北省食品安全風(fēng)險(xiǎn)評(píng)估專家組專家.
主要學(xué)術(shù)成果：獲省級(jí)科技進(jìn)步獎(jiǎng)3項(xiàng)、省/校級(jí)高教優(yōu)秀成果獎(jiǎng)2項(xiàng)，在權(quán)威期刊上發(fā)表科研論文120余篇，其中SCI收錄30余篇。主編或參編人民衛(wèi)生出版社教材6部、其他專著5部.
主要研究課題：
1.國(guó)家自然基金面上項(xiàng)目：CD147-MCTs調(diào)控乳酸穿梭在低劑量鉛致睪丸細(xì)胞毒性中的作用研究（批準(zhǔn)號(hào)：81773471,2018.01-2021.12）
2.國(guó)家自然基金面上項(xiàng)目：MRP1/MRP2-GSH在睪丸細(xì)胞鉛轉(zhuǎn)運(yùn)中的作用研究（批準(zhǔn)號(hào)：81172628, 2012.1-2015.12）
部分代表性論文：
1. Yu J, Sun J, Fan Y, Su J, Xie J, Wu Y, Liu X, Wang C*. Exposure to Pb and Cd alters MCT4/CD147 expression and MCT4/CD147-dependent lactate transport in mice Sertoli cells cultured in vitro. Toxicol In Vitro. 2019 Apr;56:30-40. doi: 10.1016/j.tiv.2019.01.001.
2. Fan Y, Yu G, Yu J, Sun J, Wu Y, Zhao X, Meng Y, He Z, Wang C*. Research Trends and Hotspots Analysis Related to the Effects of Xenobiotics on Glucose Metabolism in Male Testes. Int J Environ Res Public Health. 2018 Jul 26;15(8). pii: E1590. doi: 10.3390/ijerph15081590
3. Liu C, Liu Y, Zhou Y, Feng A, Wang C*, Shi T*. Short-term effect of relatively low level air pollution on outpatient visit in Shennongjia, China.Environ Pollut. 2018 Oct 30;245:419-426. doi: 10.1016/j.envpol.2018.10.120
4. Sun J, Yu G, Zhang Y, Liu X, Du C*, Wang L, Li Z, Wang C. Heavy Metal Level in Human Semen with Different Fertility: a Meta-Analysis. Biol Trace Elem Res. 2017 Mar;176(1):27-36.
5. Liu X, Ye J, Wang L, Li Z, Zhang Y, Sun J, Du C, Wang C*, Xu S*. Protective Effects of PGC-1α Against Lead-Induced Oxidative Stress and Energy Metabolism Dysfunction in Testis Sertoli Cells. Biol Trace Elem Res. 2017 Feb;175(2):440-448.
6. Li Z, Liu X, Wang L, Wang Y, Du C, Xu S, Zhang Y, Wang C*, Yang C*. The role of PGC-1α and MRP1 in lead-induced mitochondrial toxicity in testicular Sertoli cells.Toxicology. 2016 Apr 29;355-356:39-48. doi: 10.1016/j.tox.2016.05.016
7. Ye J, Du C, Wang L, Li Z, Huang S, Wang H, He L, Bi Y, Wang C*. Relationship of blood levels of Pb with Cu, Zn, Ca, Mg, Fe, and Hb in children aged 0 ～ 6 years from Wuhan, China. Biol Trace Elem Res. 2015 Mar;164(1):18-24. doi: 10.1007/s12011-014-0200-8
8. Li Z, Wang H, Huang S, Zhou L, Wang L, Du C, Wang C*. Establishment of stable MRP1 knockdown by lentivirus-delivered shRNA in the mouse testis Sertoli TM4 cell line. Toxicol Mech Methods. 2015 Feb;25(2):81-90. doi: 10.3109/15376516.2014.989350.
9. Shaoxin Huang, Jingping Ye, Jun Yu, Li Chen, Langhuan Zhou, Hong Wanga,Zhen Li, Chunhong Wang*. The accumulation and efflux of lead partly depend on ATP-dependent efflux pump–multidrug resistance protein 1 and glutathione in testis Sertoli cells. Toxicology Letters. 226 (2014) 277–284. doi: 10.1016/j.toxlet.2014.02.017.
10. Wang Y, Fang J, Huang S, Chen L, Fan G, Wang C*: The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. Environ Toxicol Pharmacol 2013, 35(1):109-116. doi: 10.1016/j.etap.2012.12.001.
